The gene for the major intrinsic protein (MIP) of the ocular lens is assigned to human chromosome 12cen-q14.
نویسندگان
چکیده
The gene for the human major intrinsic protein (MIP) of the ocular lens fiber membrane has been assigned to region cen-q14 of chromosome 12 through the use of somatic cell hybrids containing the whole chromosome and parts of human chromosome 12.
منابع مشابه
I-49: Human Y Chromosome ProteomeProject
The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...
متن کاملRegional Assignment of the Rat Alpha-Feto Protein Gene (Afp) to Chromosome 14p21-p22
The gene encoding alpha fetoprotein (locus symbol Afp) was assigned to rat chromosome 14 at band p21-p22 using fluorescence in situ hybridization method. The present result suggests that there is a conserved syntenic group between human 4q11-q13, mouse 5F-G, and rat 14p21-p22.
متن کاملI-3: Human Y Chromosome Proteome Project 2012 Update
The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...
متن کاملI-39: Exploring New Frontiers in Human Y Chromosome Proteome Project
The major goal of the Chromosome-Centric Human Proteome Project (C-HPP) is to systematically map the entire human proteome with the intent to enhance our understanding of human biology at the cellular level. However, this goal may be hindered by the lack of quality observations of given proteins due to absence of expression in a given tissue, very low abundance, and expression only in rare samp...
متن کاملA new locus for autosomal dominant cataract on chromosome 12q13.
PURPOSE To map the gene for autosomal dominant cataracts (ADC) in an American white family of European descent. METHODS Ophthalmic examinations and linkage analyses using a variety of polymorphisms were performed; two-point lod scores calculated. RESULTS Affected individuals (14 studied) exhibited variable expressivity of embryonal nuclear opacities based on morphology, location within the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Investigative ophthalmology & visual science
دوره 27 9 شماره
صفحات -
تاریخ انتشار 1986